Yes he does. Draco is his nephew. Nacrissa Malfoy (nee black) is Sirius' cousin along with Bellatrix Lestrange and Andromeda Tonks. Sirius Black and Narcissa Malfoy were fist cousins by relation but had bitter feelings against each other.
All pure-blood families are inter-related. James Potter and Sirius were best friends, but they are also distant cousins.